Combined European Cohorts
Six different cohorts, totaling 73,881 mother-child pairs
Scientists asked mothers about their acetaminophen use while pregnant and then assessed whether those children have autism based on the Childhood Autism Spectrum Test, the Child Behavior Checklist, and the Strengths and Difficulties Questionnaire between ages 6 and 13. This meta-analysis found about a 20% increase in the chance of having a child with neurodevelopmental issues if they had been exposed to acetaminophen prior to birth. Boys in this cohort were more likely to have autism than girls.